Why Sertraline to treat premature ejaculation?

Sertraline, the active ingredient in Zoloft, is a selective serotonin reuptake inhibitor (SSRI) that helps increase the serotonin levels in your brain. Since serotonin is part of how your brain processes sexual excitement, SSRIs like sertraline can help manage premature ejaculation during the times that count, without numbing the penis.

The SSRI class of drugs, including Sertraline, is FDA-approved to treat depression, anxiety and certain other mood disorders. Treatment for premature ejaculation is an “off-label” use of Sertraline.

How to use?

Sertraline for premature ejaculation is taken daily. Simply take your medication at the
same time every day with or without food. Always take sertraline exactly as prescribed
by your doctor.

How MaleMD works


Online visit

Share your symptoms and medical history in the free online visit. A US-licensed healthcare provider will review your information and will typically get back to you within 24 hours.


Free and discreet deliveries

If prescribed, your treatment will arrive at your door in discreet packaging.


Ongoing care

Send your provider a message at any time to discuss updating your treatment, address side effects, or answer other treatment-related questions or concerns.

Important safety

Frequesntly Asked

Premature ejaculation (or "PE," for short) is defined as a "persistent or recurrent ejaculation with minimal stimulation before, on or shortly after penetration and before the person wishes it. In simple terms, premature ejaculation occurs when you ejaculate too early during intercourse or sexual activity. There’s no specific amount of time that defines ejaculation as "premature"—most sources use figures ranging from 30 seconds to four minutes into sexual activity.

Start Free Online Visit

Sertraline is in a class of drugs called SSRIs. Urology experts believe serotonin helps control ejaculation timing. Low serotonin levels may mean ejaculation happens faster. Since sertraline raises serotonin levels, it can help lengthen the time before ejaculation happens.

Start Free Online Visit

Premature Ejaculation is more common than you’d expect. AccorPerform Any Time on Demand!ding to the Mayo Clinic, studies vary, but it’s estimated that as many as 1 out of 3 men 18 to 59 years old experience PE at some time.

Start Free Online Visit

A U.S. licensed doctor will review the answers your medical intake form within 2 hours during normal business operations and usually less 24 hours during non-business hours. We know that now that you have made your choice to begin treating your E.D., you’re very anxious to get started. We fully understand this and will review your prescription as quickly as possible. Once your prescription has been approved by one of our doctors, and your card has been billed, our pharmacy will ship out your medication to you that same day via USPS First Class Mail.

Start Free Online Visit

Your prescription for selected medication is good for 12 months if it is approved by one of our Doctors. During this time, you have access to communicate with your Doctor via the MaleMD website. You can also contact our care team 24/7 to process any refills or adjust your billing schedule as you wish.

Start Free Online Visit

MaleMD accepts Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA).

Using your HSA/FSA is easy. Simply use your HSA/FSA card as you would any other debit or credit card when providing your billing information.

HSA/FSA plans vary on what services they are willing to cover. If you are uncertain whether your plan covers MaleMD's services, check with your plan administrator.

Start Free Online Visit

© Copyright 2024, MaleMD | 16192 Coastal Hwy, Lewes, DE 19958 | Phone Number: 888-294-9877