Prescription Pain Relief — Applied Where It Hurts

MaleMD Precision Pain Relief Gel is a topical treatment formulated with ketorolac (a non-steroidal anti-inflammatory drug, or NSAID), DMSO (a penetration enhancer), and olive oil in a VersaPro gel base. It’s designed to be applied directly to the skin to help relieve localized pain and inflammation in muscles, joints, and soft tissues.

Ketorolac works by blocking chemicals in the body that cause pain and inflammation, helping reduce discomfort at the application site. Because it’s applied to the skin, it targets the painful area directly and reduces systemic exposure compared with oral NSAIDs.

People commonly use it for relief from:

• Muscle aches and strains
• Joint pain (e.g., knees, shoulders)
• Soft tissue injuries
• Tendonitis
• Pain from mild arthritis flare-ups

Clean and dry the application area on the skin. Apply a thin layer and gently rub it in, unless instructed by your doctor to apply a thick layer. Only use on clean, intact skin—do not apply over cuts, wounds, or broken skin.

Avoid tight bandages or occlusive dressings over the treated area unless your doctor tells you otherwise, as this can increase absorption and the risk of side effects.

Some users report noticing relief within 15–30 minutes after application, while others may need more time. Individual experiences vary based on the area treated and severity of discomfort.

Because this gel is applied to the skin, systemic side effects (like stomach upset) are much less common than with oral pain relievers. However, local reactions can occur, such as:

• Skin irritation or redness
• Rash or itching.
  (If irritation persists or worsens, stop use and consult a healthcare provider.)

Yes. Although topical administration reduces systemic absorption, ketorolac is still an NSAID and can potentially cause NSAID-related effects—especially with prolonged use or over large areas. Talk to your doctor if you have a history of NSAID sensitivity.

Avoid if you:

• Are allergic to ketorolac or other NSAIDs (e.g., ibuprofen, aspirin)
• Have active skin infections, open wounds, or broken skin at the application site
• Are pregnant or breastfeeding (consult your doctor)
• Have a history of NSAID-related complications (e.g., stomach ulcers, kidney issues) If you have serious health conditions, check with a healthcare provider before use.

Do not apply other topical NSAIDs (like diclofenac or ibuprofen gels) to the same area at the same time, as this increases the amount of NSAID exposure. Tell your provider about all medications you use—both topical and oral.